Xylazine disrupts skin homeostasis

Evidence that xylazine disrupts skin homeostasis by acting on epithelial cells through the kappa opioid receptor.

Robertson TF, Horn A, Smith FM, Huttenlocher A.Dis Model Mech. 2026 Mar 1;19(3):dmm052600. doi: 10.1242/dmm.052600. Epub 2026 Mar 31.PMID: 41788025