The Aspergillus fumigatus C2-Domain Protein SppA is required for septal integrity and alters susceptibility to echinocandins and neutrophil killing during infection. Calise DG, Michaelis ML, Bok JW, Chen Z, Coon JJ, Huttenlocher A, Chadwick BJ, Keller NP.bioRxiv [Preprint]. 2026 Jul 20:2026.07.17.739181. doi: 10.64898/2026.07.17.739181.PMID: 42539235
Fibroblast response to burn injury in larval zebrafish mirrors developmental maturation and is inhibited by infiltrating neutrophils. Horn A, Hou Y, Squirrell JM, Fister AM, Rindy J, Miskolci V, Schrope JH, Burke R, Dewey C, Eliceiri KW, Huttenlocher A.Development. 2026 Aug 1;153(15):dev205534. doi: 10.1242/dev.205534. Epub 2026 Aug 6.PMID: 42464766
Evidence that xylazine disrupts skin homeostasis by acting on epithelial cells through the kappa opioid receptor. Robertson TF, Horn A, Smith FM, Huttenlocher A.Dis Model Mech. 2026 Mar 1;19(3):dmm052600. doi: 10.1242/dmm.052600. Epub 2026 Mar 31.PMID: 41788025
The paracrine factor myeloid derived growth factor regulates the inflammatory fate and motility of human induced pluripotent stem cell-derived neutrophils. Smith FM, Schrope JH, Bennin DA, Horn A, Wagner AS, Hou Y, Stevens JJ, Giese MA, Dinh HQ, Huttenlocher A.J Immunol. 2026 Feb 9;215(2):vkaf364. doi: 10.1093/jimmun/vkaf364.PMID: 41764731
Best wishes to Jayne Squirrell on her retirement. The lab will miss you!